Annual abundance indices and run timing of adult Chinook Oncorhynchus tshawytscha, sockeye O. nerka, chum O. keta, and coho O. kisutch salmon returning to the Kuskokwim River have been assessed by the Bethel drift gillnet test fishery since 1984. In 2010, the Bethel salmon test fishery operated from June 1 through August 24. A series of timed drifts using 5.375 in (13.6 cm) and 8.0 in (20.3 cm) stretch mesh gillnets were made at three stations across the river channel. Each series of drifts began approximately one hour following each high tide throughout the fishing season. Mean tidal catch per unit effort (CPUE) that served as an index of abundance was calculated for each species. The cumulative mean tidal CPUE was compared to information from earlier years and to the results from the Lower Kuskokwim inseason subsistence salmon harvest monitoring project to determine salmon abundance and run timing to help direct subsistence and commercial management decisions. The final cumulative CPUE index through August 24 was: Chinook salmon 461, sockeye 1,374, chum 7,651, and coho salmon 2,024. Relative abundance indices were below the 2000–2009 averages for Chinook, sockeye and coho salmon while chum salmon was near average. Run timing of Chinook salmon peaked a day early on June 21; sockeye salmon peaked nine days late on 7 July; chum peaked two days late on 7 July; and coho salmon were on time and peaked on August 7.